Choice. 5.572 Impact Factor. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization, Discovery of novel anti-angiogenesis agents. Over the past decade, diverse metalloprotein inhibitors have been reported, most of which are mimics of metalloprotein substrates. Submit your article. Chem. Articles & Issues. This special issue provided a broad overview of progresses that have been made in the discovery and development of metalloprotein inhibitors and attempt to map out the current landscape of high-value metalloprotein targets. In partnership with the communities we serve; we redouble our deep commitment to inclusion and diversity within our editorial, author and reviewer networks. Help expand a public dataset of research that support the SDGs. Medicinal chemistry journal target Researchers, Scientists, and Students who seek to advance the technical knowledge and practical applications related to pharmaceutical chemistry. To decline or learn more, visit our Cookies page. 不论您是正在查找出版流程的信息还是忙于撰写下一篇稿件,我们都随时待命。下面我们将重点介绍一些可以在您的科研旅程中对您提供支持的工具。, Below is a recent list of 2019—2020 articles that have had the most social media attention. To decline or learn more, visit our Cookies page. Sung Jin Cho, https://doi.org/10.1016/j.ejmech.2020.112664, Man Li, Lan Yuan, Yingying Chen, Wenxiao Ma, ... Sulong Xiao, https://doi.org/10.1016/j.ejmech.2020.112616, Li-Yan Zeng, Fubiao Yang, Kaixuan Chen, Yunong Zeng, ... Baomin Xi, https://doi.org/10.1016/j.ejmech.2020.112654, Yuanyuan Shan, Ru Si, Jin Wang, Qingqing Zhang, ... Jie Zhang, https://doi.org/10.1016/j.ejmech.2020.112629, Mingliang Zhang, Shufeng Li, Hang Zhang, Haiwei Xu, https://doi.org/10.1016/j.ejmech.2020.112669, Maria Chiara Pismataro, Nicole A. Horenstein, Clare Stokes, Marta Quadri, ... Clelia Dallanoce, https://doi.org/10.1016/j.ejmech.2020.112662, Ahmed H. Abdelazeem, Asmaa G. Safi El-Din, Maha M. Abdel-Fattah, Noha H. Amin, ... Mohammed T. El-Saadi, https://doi.org/10.1016/j.ejmech.2020.112537, Zhanhui Li, Xu Wang, Yu Lin, Yujie Wang, ... Xiaohu Zhang, https://doi.org/10.1016/j.ejmech.2020.112663, Ting Xu, Zhiyuan Zheng, Yong Guo, Li-Ping Bai, https://doi.org/10.1016/j.ejmech.2020.112648, Dahong Yao, Chenyang Li, Jin Jiang, Jian Huang, ... Jin Zhang, https://doi.org/10.1016/j.ejmech.2020.112581, Jingying Qiu, Qingqing Zhou, Yinpeng Zhang, Mingyu Guan, ... Xiaoke Gu, https://doi.org/10.1016/j.ejmech.2020.112638, Philippe Gilles, Rudra S. Kashyap, Maria João Freitas, Sam Ceusters, ... Wim M. De Borggraeve, https://doi.org/10.1016/j.ejmech.2020.112649, Mengdi Zhang, Zhaoxin Wang, Siyu Hao, Lei Hao, ... Hua Sun, https://doi.org/10.1016/j.ejmech.2020.112645, Bin Sun, Yue Dong, Yunfei An, Min Liu, ... Xinyong Liu, https://doi.org/10.1016/j.ejmech.2020.112642, Subha Mondal, Nilanjan Adhikari, Suvankar Banerjee, Sk Abdul Amin, Tarun Jha, https://doi.org/10.1016/j.ejmech.2020.112611, Marek Bajda, Dorota Łażewska, Justyna Godyń, Paula Zaręba, ... Barbara Malawska, https://doi.org/10.1016/j.ejmech.2020.112899, https://doi.org/10.1016/S0223-5234(20)30853-9, https://doi.org/10.1016/S0223-5234(20)30854-0, select article Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors, Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors, select article New drug approvals for 2019: Synthesis and clinical applications, New drug approvals for 2019: Synthesis and clinical applications, select article An insight on medicinal attributes of 1,2,4-triazoles, An insight on medicinal attributes of 1,2,4-triazoles, select article Potential treatment methods targeting 2019-nCoV infection, Potential treatment methods targeting 2019-nCoV infection, select article Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis, Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis, select article Bicyclic polyprenylated acylphloroglucinols and their derivatives: structural modification, structure-activity relationship, biological activity and mechanism of action, Bicyclic polyprenylated acylphloroglucinols and their derivatives: structural modification, structure-activity relationship, biological activity and mechanism of action, select article Hydroxamic acid hybrids as the potential anticancer agents: An Overview, Hydroxamic acid hybrids as the potential anticancer agents: An Overview, select article Recent advancements in the development of bioactive pyrazoline derivatives, Recent advancements in the development of bioactive pyrazoline derivatives, select article Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors, Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors, select article (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis, select article Design, synthesis and in vivo evaluation of 3-arylcoumarin derivatives of rhenium(I) tricarbonyl complexes as potent antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA), select article A cell-penetrant lactam-stapled peptide for targeting eIF4E protein-protein interactions, A cell-penetrant lactam-stapled peptide for targeting eIF4E protein-protein interactions, select article Synthesis and in vitro anti-bladder cancer activity evaluation of quinazolinyl-arylurea derivatives, select article An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer, An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer, select article Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes, Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes, select article The one-pot synthesis of butyl-1H-indol-3-alkylcarboxylic acid derivatives in ionic liquid as potent dual-acting agent for management of BPH, select article Discovery of novel anti-angiogenesis agents.

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